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Genome Editing Helps Cell Lines

Genetic Engineering & Biotechnology News | May 5, 2020

If you want to "clean up" in the recombinant protein business, you might want to start by sweeping away process-related impurities, specifically, host cell proteins (HCPs). Undesirable HCPs are generated by host cells along with desirable biotherapeutic proteins, increasing metabolic demand, degrading product quality, and contaminating the final product. They also necessitate troublesome (and expensive) purification procedures. In other words, you can clean up now, or clean up later. To make "now" an option, researchers from the University of California, San Diego (UCSD) Full Story